From epigenetics to metastasis: Multifaceted roles of lncRNAs in gastric cancer

Mohamed J Saadh, Ashok Kumar Bishoyi, R Roopashree, K Satyam Naidu, Lokesh Verma, Ojas Prakashbhai Doshi, Piyus Kumar Pathak, Suman Saini, Fadhil Faez Sead · 2026

Read From epigenetics to metastasis: Multifaceted roles of lncRNAs in gastric cancer by Mohamed J Saadh, Ashok Kumar Bishoyi, R Roopashree, K Satyam Naidu, Lokesh Verma, Ojas Prakashbhai Doshi, Piyus Kumar Pathak, Suman Saini, Fadhil Faez Sead (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-13571509.txt.

Description

Mohamed Saadh and eight co-authors review how long non-coding RNAs help stomach cancer spread. Their 2026 review covers RNA strands that do not build proteins yet steer gene activity at many levels. Stomach cancer kills many patients worldwide, largely because it spreads early and resists treatment. A key step is a shape-shift that lets tumor cells move and invade.

These RNAs act as gene-silencing guides, as decoys that soak up smaller RNAs, and as scaffolds that gather protein machines. Through them they tune the pathways that drive the shape-shift, among them Wnt, PI3K, and NF-kB routes. They also reshape the tumor's neighborhood, its blood supply, and its dealings with the immune system. Because their levels track with patient outcomes, they may serve as markers. Drugs aimed at them could fight spread and resistance.

Catalog record

CREATORMohamed J Saadh, Ashok Kumar Bishoyi, R Roopashree, K Satyam Naidu, Lokesh Verma, Ojas Prakashbhai Doshi, Piyus Kumar Pathak, Suman Saini, Fadhil Faez Sead
YEAR2026
COLLECTIONPAPERS
FORMATTXT
FILE SIZE66 KB
VERSION1.0
LICENSECC BY 4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/articles/PMC13571509

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