Tumor regression grades in locally advanced gastroesophageal adenocarcinoma: associations with survival, pathological risk factors, and molecular biomarkers in a 19-year real-world cohort
H.C. Puhr, B. Mozayani, M. Korpan, M. Kaya, F. Kordik, M. Kastner, A. Duman, G. Jomrich, D. Kollmann, S.F. Schoppmann, J.M. Berger, G.W. Prager, E.S. Bergen, M. Preusser, A. Ilhan-Mutlu · 2026
Read Tumor regression grades in locally advanced gastroesophageal adenocarcinoma: associations with survival, pathological risk factors, and molecular biomarkers in a 19-year real-world cohort by H.C. Puhr, B. Mozayani, M. Korpan, M. Kaya, F. Kordik, M. Kastner, A. Duman, G. Jomrich, D. Kollmann, S.F. Schoppmann, J.M. Berger, G.W. Prager, E.S. Bergen, M. Preusser, A. Ilhan-Mutlu (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-13571382.txt.
Description
Puhr and co-authors study tumor regression grades, scores for how much a stomach or gullet tumor shrank after drug treatment, in a 19 year real world cohort. Such grades have been pitched as a sign of patient outlook, but their worth past standard staging was unclear. Their 2026 study ran at one center in Vienna.
The cohort held 692 patients with locally advanced, operable disease treated from 2006 to 2024. Of 394 who got drug treatment first, 175 had a documented grade. Poor response was the most common pattern. Lower grades, meaning more shrinkage, tied strongly to better stage scores after treatment. They also tied to no spread into lymph, vein, or nerve paths.
Catalog record
| CREATOR | H.C. Puhr, B. Mozayani, M. Korpan, M. Kaya, F. Kordik, M. Kastner, A. Duman, G. Jomrich, D. Kollmann, S.F. Schoppmann, J.M. Berger, G.W. Prager, E.S. Bergen, M. Preusser, A. Ilhan-Mutlu |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 37 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |