Methodological considerations on immunoadsorption versus sham treatment for post-COVID syndrome

Kamyar Mansori, Mojtaba Soltani-Kermanshahi · 2026

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Description

Kamyar Mansori and Mojtaba Soltani-Kermanshahi raise points in a 2026 letter on a trial of blood filtering for post-COVID illness. The trial swapped patients between true filtering, which pulls out self-attacking proteins, and a sham run, to see if symptom load fell. The letter team asks if the swap plan was guarded well enough.

A swap trial can blur results when the first care keeps acting in the next phase, they note. A rest gap can prevent that blur, but the study did not set one out. They also saw no test for such carry-over effects, though old guides urge one at the start. No checks that the data fit a bell curve were shown either. These gaps, they say, should temper how the results are read.

Catalog record

CREATORKamyar Mansori, Mojtaba Soltani-Kermanshahi
YEAR2026
COLLECTIONPAPERS
FORMATTXT
FILE SIZE2 KB
VERSION1.0
LICENSECC BY 4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/articles/PMC13571250

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