Changes in Serum GDF-15 in Relation to the Onset of Post-Stroke Depression After Acute Ischemic Stroke and the Development of a Comprehensive Prediction Model
Chengzhi Guo, Xiuyan Liu, Yu Yun, Zhihuan Mi · 2026
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Description
Chengzhi Guo, Xiuyan Liu, Yu Yun, and Zhihuan Mi study depression after stroke in a 2026 paper. They ask whether a blood protein called GDF-15, measured on arrival, helps predict which patients will develop low mood after a stroke caused by a clot.
Records of three hundred two patients at one Chinese hospital were compared. One hundred developed depression after the stroke and the rest did not. The depression group was older, had worse stroke scores, and showed higher levels of GDF-15 and several other blood markers. A model built from the risk factors was drawn as a nomogram and checked for how well it sorted patients.
Catalog record
| CREATOR | Chengzhi Guo, Xiuyan Liu, Yu Yun, Zhihuan Mi |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 28 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |