Clinical efficacy of an extended local treatment in nasal polyps with different endotypes: A prospective randomized controlled study☆

Ziqi Huang, Zhaofeng Xu, Wufuerjiang Yiming, Tingyan Wang, Xiaolin Chen, Jianbo Shi, Yinyan Lai · 2026

Read Clinical efficacy of an extended local treatment in nasal polyps with different endotypes: A prospective randomized controlled study☆ by Ziqi Huang, Zhaofeng Xu, Wufuerjiang Yiming, Tingyan Wang, Xiaolin Chen, Jianbo Shi, Yinyan Lai (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-13571130.txt.

Description

Ziqi Huang and co-authors compare steroid deliveries for nasal polyps in a 2026 trial. Nasal polyps are soft growths inside the nose that come with long-term sinus inflammation. Steroids shrink them, but the best way to give the drug, and the best length of treatment, were open questions. The trial also split patients by disease type, called endotype.

One hundred thirty-eight patients were assigned at random to spray alone, spray plus drops, or spray plus oral steroid pills, for two weeks. The drops group eased symptoms more than spray alone, above all blocked nose and thick discharge, and matched the pills group. Oral steroids shrank polyps most, above all in the type-two form of the disease. Stretching care from one week to two helped some groups in distinct ways. The authors weigh symptom relief against polyp shrinkage by method.

Catalog record

CREATORZiqi Huang, Zhaofeng Xu, Wufuerjiang Yiming, Tingyan Wang, Xiaolin Chen, Jianbo Shi, Yinyan Lai
YEAR2026
COLLECTIONPAPERS
FORMATTXT
FILE SIZE33 KB
VERSION1.0
LICENSECC BY 4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/articles/PMC13571130

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