Characterization of PAPP-A Patterns in Chronic Rhinosinusitis
Afaf Ennahal, Olaf Wendler, Vanessa Vivien Pesold, Sarina Katrin Mueller · 2026
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Description
Afaf Ennahal and colleagues mapped where a protein called PAPP-A appears in chronic sinus disease in a study published in two thousand twenty-six. Earlier work showed high levels in sinus disease with nasal polyps, and the protein matters in inflammation and cancer. They stained tissue from patients with and without polyps, plus healthy controls.
Staining patterns in polyp tissue tracked with counts of eosinophil immune cells. Those cells made the protein strongly, along with some T cells and mast cells, and levels in mucus matched a related inflammation marker. Sinus specialists gain a candidate signal for sorting patients by inflammation type.
Catalog record
| CREATOR | Afaf Ennahal, Olaf Wendler, Vanessa Vivien Pesold, Sarina Katrin Mueller |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 34 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |