Grading the evidence for the association between periodontal disease and chronic non-communicable diseases: an umbrella review of meta-analyses of observational studies
Haozhu Liu, Xiao Bai, Yuanfang Wang, Dongqiu Dai · 2026
Read Grading the evidence for the association between periodontal disease and chronic non-communicable diseases: an umbrella review of meta-analyses of observational studies by Haozhu Liu, Xiao Bai, Yuanfang Wang, Dongqiu Dai (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/PMC13570550.txt.
Description
Haozhu Liu and co-authors grade, in a 2026 umbrella review, claims linking gum disease to chronic diseases such as cancer and heart disease. Thirty-eight earlier meta-analyses covering fifty-eight links across nine disease groups were rechecked for quality, consistency, and bias with standard credibility tools.
Most links reached statistical significance, yet few stayed convincing once prediction ranges and between-study variation were considered. Only four links reached the highly suggestive tier, covering a stomach bacterium infection and three cancer groupings, and none rested on a top-quality meta-analysis. Readers get a sobering scale for claims that gum disease causes widespread illness.
Catalog record
| CREATOR | Haozhu Liu, Xiao Bai, Yuanfang Wang, Dongqiu Dai |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 64 KB |
| LICENSE | https://creativecommons.org/licenses/by/4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |