Combined Effect of Silybin and Sodium Acetylated Hyaluronate on UV‐Induced Photoaging
Sen Hou, Hanliang Song, Jianying Zhang, Anzhang Li · 2026
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Description
Sen Hou and co-authors test whether two known skin compounds protect better together against sun-driven aging. Ultraviolet light drains collagen from skin, causing photoaging. Silybin, from milk thistle, and a modified hyaluronate each help a little on their own, but alone their effect is limited.
In cell tests with and without ultraviolet exposure, the pair was checked for safety across doses. The team measured collagen-building genes, the collagen-chewing enzyme MMP-1, and how well the mix mops up reactive oxygen. Combined use lifted collagen signals and curbed breakdown more than single agents suggest. A two-part shield may suit sunscreens and anti-aging creams better than either part alone.
Catalog record
| CREATOR | Sen Hou, Hanliang Song, Jianying Zhang, Anzhang Li |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 29 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |