Safety Profile of Nebulized Ciprofloxacin‐Dexamethasone After Pediatric Airway Surgery

Abbey L Landini, Cyrus W Abrahamson, Maya Frost, David Spielberg, Inbal Hazkani, Dana M Thompson, Jonathan B Ida, Sarah Maurrasse, Taher Valika · 2026

Read Safety Profile of Nebulized Ciprofloxacin‐Dexamethasone After Pediatric Airway Surgery by Abbey L Landini, Cyrus W Abrahamson, Maya Frost, David Spielberg, Inbal Hazkani, Dana M Thompson, Jonathan B Ida, Sarah Maurrasse, Taher Valika (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-13569635.txt.

Description

Abbey L Landini's team checked the safety of nebulised ciprofloxacin-dexamethasone after children's airway surgery, in a 2026 retrospective review. The antibiotic-steroid mix, borrowed from ear care, is widely used off-label to calm swelling and granulation after airway operations, yet rigorous safety data were lacking. The team reviewed 399 children treated at a tertiary centre between 2019 and 2023, most after surgery for narrowing below the vocal cords.

Children received the inhaled drug for about twelve days on average, and no cases of adrenal suppression, glucose disturbance, or airway over-reactivity appeared. One child on chemotherapy had suspected fungal infection with negative pathology, and endoscopy showed no major swelling. The authors judge the drug well tolerated in medically complex children while calling for prospective trials of benefit and dosing.

Catalog record

CREATORAbbey L Landini, Cyrus W Abrahamson, Maya Frost, David Spielberg, Inbal Hazkani, Dana M Thompson, Jonathan B Ida, Sarah Maurrasse, Taher Valika
YEAR2026
COLLECTIONPAPERS
FORMATTXT
FILE SIZE18 KB
VERSION1.0
LICENSECC BY 4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/articles/PMC13569635

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