Ionic characteristics and osmolarity of cooling fluid in hepatic laser ablation: a 7T MRI-based comparison in ex vivo bovine liver
Fiona Mankertz, Josephine Berger, Nour Maalouf, Benedikt Stenzl, Antonia Ashkar, Ole Gemeinhardt, Johannes Uhlig, Saif Afat, Norbert Hosten, Judith Herrmann · 2026
Read Ionic characteristics and osmolarity of cooling fluid in hepatic laser ablation: a 7T MRI-based comparison in ex vivo bovine liver by Fiona Mankertz, Josephine Berger, Nour Maalouf, Benedikt Stenzl, Antonia Ashkar, Ole Gemeinhardt, Johannes Uhlig, Saif Afat, Norbert Hosten, Judith Herrmann (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-13569545.txt.
Description
Fiona Mankertz and co-authors compare cooling fluids for laser tumor ablation in liver tissue in a 2026 study. Burning liver tumors with a laser probe needs internal cooling, and the fluid's salt content might change how heat spreads. Three fluids with different ionic strength and osmolarity were put head to head.
Thirty-six ablations in five cow livers used saline, sugar water, or mannitol as the coolant, with burn zones measured on high-field MRI. Mannitol produced clearly larger ablation volumes than either rival, by about two cubic centimeters, and wider burns to match. Two measurement methods agreed closely. The authors caution that dead tissue is not a patient, but flag fluid choice as a real dial on ablation size worth clinical study.
Catalog record
| CREATOR | Fiona Mankertz, Josephine Berger, Nour Maalouf, Benedikt Stenzl, Antonia Ashkar, Ole Gemeinhardt, Johannes Uhlig, Saif Afat, Norbert Hosten, Judith Herrmann |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 43 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |