Effectiveness of continuous pharmacist intervention at maintaining dose intensity in postoperative adjuvant S-1 chemotherapy for gastric cancer: a multicentre retrospective study

Toshinobu Hayashi, Makiko Go, Kenji Kawasumi, Kazuyoshi Kawakami, Reiko Matsui, Hironori Fujii, Takanori Miyoshi, Tomoaki Eto, Makoto Kajizono, Tatsuya Ohtsubo, Yumi Morioka, Kyohei Yamaguchi, Akihiro Ogawa, Toshihisa Nakashima, Maki Todo, Koichi Matsuo · 2026

Read Effectiveness of continuous pharmacist intervention at maintaining dose intensity in postoperative adjuvant S-1 chemotherapy for gastric cancer: a multicentre retrospective study by Toshinobu Hayashi, Makiko Go, Kenji Kawasumi, Kazuyoshi Kawakami, Reiko Matsui, Hironori Fujii, Takanori Miyoshi, Tomoaki Eto, Makoto Kajizono, Tatsuya Ohtsubo, Yumi Morioka, Kyohei Yamaguchi, Akihiro Ogawa, Toshihisa Nakashima, Maki Todo, Koichi Matsuo (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/PMC13569544.txt.

Description

Toshinobu Hayashi leads a 2026 multicentre retrospective study of whether continuous pharmacist support keeps gastric cancer patients on full-dose S-1 chemotherapy after surgery. Records for 225 patients at twelve institutions compared ongoing pharmacist monitoring for at least half the treatment against less regular contact, with statistics adjusted for starting differences.

Completion of all eight cycles was nearly identical between groups, near fifty-four percent, and dose changes were equally common. Patients with continuous support, though, maintained a higher share of their planned dose over time. The benefit is about dose intensity rather than finishing, a distinction that matters when judging pharmacy services in cancer care.

Catalog record

CREATORToshinobu Hayashi, Makiko Go, Kenji Kawasumi, Kazuyoshi Kawakami, Reiko Matsui, Hironori Fujii, Takanori Miyoshi, Tomoaki Eto, Makoto Kajizono, Tatsuya Ohtsubo, Yumi Morioka, Kyohei Yamaguchi, Akihiro Ogawa, Toshihisa Nakashima, Maki Todo, Koichi Matsuo
YEAR2026
COLLECTIONPAPERS
FORMATTXT
FILE SIZE32 KB
LICENSEhttps://creativecommons.org/licenses/by/4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/article/MED/PMC13569544

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