Hospital-treated infection associated with Alzheimer’s disease pathology: underlying mechanisms
Tatiana Barichello, Giselli Scaini, Mohd Tayyab, Henrique Ritter Dal-Pizzol, Fabricia Petronilho, Felipe Dal-Pizzol · 2026
Read Hospital-treated infection associated with Alzheimer’s disease pathology: underlying mechanisms by Tatiana Barichello, Giselli Scaini, Mohd Tayyab, Henrique Ritter Dal-Pizzol, Fabricia Petronilho, Felipe Dal-Pizzol (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/PMC13569452.txt.
Description
Tatiana Barichello and colleagues review, in a 2026 expert article, how infections treated in hospital may feed the brain changes of Alzheimer's disease. Large population studies, brain tissue work, and animal experiments are combined to trace how body-wide and brain infections stir immune alarms that damage the blood-brain barrier and inflame brain tissue.
Activated immune sensors can release particles that seed clumping of amyloid and tau, the hallmark proteins of the disease, while one infection-linked protein boosts the enzyme that makes amyloid. The chain positions infection as an upstream trigger rather than a bystander. Researchers get a mechanistic map for testing whether preventing or treating infections can slow dementia.
Catalog record
| CREATOR | Tatiana Barichello, Giselli Scaini, Mohd Tayyab, Henrique Ritter Dal-Pizzol, Fabricia Petronilho, Felipe Dal-Pizzol |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 66466 |
| LICENSE | https://creativecommons.org/licenses/by/4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |