4-Repeat Tauopathien – Progressive Supranukleäre Blickparese und kortikobasale Degeneration

Carla Teresa Palleis, Alexander Bernhardt, Günter Höglinger · 2026

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Description

Carla Teresa Palleis, Alexander Bernhardt, and Gunter Hoglinger review two brain diseases in a 2026 paper written in German. Both diseases are marked by clumps of a protein form called 4-repeat tau in the brain. Both slowly harm movement, balance, speech, thinking, and daily life.

One disease tends to strike the body axis and shrink a mid brain region, with a telling loss of up and down eye movement. The other tends to affect one side more, with shrinkage at the front and side of the brain. Since signs overlap with other diseases, telling them apart in clinic is hard. The review sorts the tissue facts from the bedside signs.

Catalog record

CREATORCarla Teresa Palleis, Alexander Bernhardt, Günter Höglinger
YEAR2026
COLLECTIONPAPERS
FORMATTXT
FILE SIZE41 KB
VERSION1.0
LICENSECC BY 4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/articles/PMC13569406

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