Soft, Reactive, and Alive: A Dynamic Framework for Degradation and Functional Stability of Polymeric Biomaterials

Alfredo Rondinella, Elia Marin · 2026

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Description

Alfredo Rondinella and Elia Marin propose, in a 2026 paper, a framework for how polymer materials used in medicine break down in the body. Such materials do not fail by one route alone. Water attack, oxidation, enzyme cutting, fatigue, wear, protein sticking, and fat uptake often act together, across the surface, the bulk, and the tissue around the implant.

The framework draws those routes as a directed network of coupled steps. It separates true breakdown reactions from surface factors that modulate them. Damage at the molecular level is then linked to how long the material keeps its function. Function is defined by the job at hand, such as strength, mass, shape, or surface performance. A qualitative matrix shows how each step can amplify or damp the next. From it, the authors name recurring breakdown patterns across major medical polymer families.

Catalog record

CREATORAlfredo Rondinella, Elia Marin
YEAR2026
COLLECTIONPAPERS
FORMATTXT
FILE SIZE112 KB
VERSION1.0
LICENSECC BY 4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/articles/PMC13568335

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