Validation of the advanced‐stage Hodgkin lymphoma international prognostic index (A‐HIPI) in the GHSG HD21 trial
Hishan Tharmaseelan, Janina Jablonski, Susan K Parsons, Angie Mae Rodday, Andrew M Evens, Josée M Zijlstra, Alexander Fosså, Daniel Molin, Mark Hertzberg, Felicitas Hitz, Martin Fehr, Richard Greil, Thomas Melchardt, Michael Fuchs, Helen Kaul, Peter Borchmann, Justin Ferdinandus · 2026
Read Validation of the advanced‐stage Hodgkin lymphoma international prognostic index (A‐HIPI) in the GHSG HD21 trial by Hishan Tharmaseelan, Janina Jablonski, Susan K Parsons, Angie Mae Rodday, Andrew M Evens, Josée M Zijlstra, Alexander Fosså, Daniel Molin, Mark Hertzberg, Felicitas Hitz, Martin Fehr, Richard Greil, Thomas Melchardt, Michael Fuchs, Helen Kaul, Peter Borchmann, Justin Ferdinandus (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-13567801.txt.
Description
A newer risk score for advanced Hodgkin lymphoma is put to the test in a 2026 validation study by Hishan Tharmaseelan and co-authors. The old score, used for over twenty years, sorts patients by seven yes-or-no factors, but modern treatment has outgrown its accuracy.
The new index was built from pooled patient data across eight trials and checked in large registries. It uses age, blood counts, and albumin as smooth scales rather than cutoffs, along with sex, stage, and bulky disease. This study checks the index inside the HD21 trial of the German Hodgkin Study Group. A sound check matters because the score steers how hard doctors treat a cancer that many patients now survive.
Catalog record
| CREATOR | Hishan Tharmaseelan, Janina Jablonski, Susan K Parsons, Angie Mae Rodday, Andrew M Evens, Josée M Zijlstra, Alexander Fosså, Daniel Molin, Mark Hertzberg, Felicitas Hitz, Martin Fehr, Richard Greil, Thomas Melchardt, Michael Fuchs, Helen Kaul, Peter Borchmann, Justin Ferdinandus |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 15 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |