Green Synthesis, Molecular Docking, and QSAR Study of Coumarin Derivatives as Acaricidal Agents Against Rhipicephalus (Boophilus) microplus
Carlos E. Rodriguez, Diego M. Ruiz, Alejandra Rodriguez, Pablo R. Duchowicz, Gustavo P. Romanelli, José J. Martínez, Laura Juliana Triana Triana · 2026
Read Green Synthesis, Molecular Docking, and QSAR Study of Coumarin Derivatives as Acaricidal Agents Against Rhipicephalus (Boophilus) microplus by Carlos E. Rodriguez, Diego M. Ruiz, Alejandra Rodriguez, Pablo R. Duchowicz, Gustavo P. Romanelli, José J. Martínez, Laura Juliana Triana Triana (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-13567135.txt.
Description
Carlos Rodriguez and co-authors make plant-derived coumarin compounds with green methods and test them against cattle ticks, in this 2026 paper. The tick species drains herds across the tropics, and chemical controls are losing ground. Coumarins offer a possible alternative chemistry.
Nine variants were built without solvent, using a reusable acid catalyst. Adult female ticks were dipped and survival was tracked with standard models. Hydroxyl-bearing variants, especially at two ring positions, killed ticks at the lowest doses. Docking and structure-activity modeling pointed to the same features: hydroxyl groups and polar side chains at one key position.
Catalog record
| CREATOR | Carlos E. Rodriguez, Diego M. Ruiz, Alejandra Rodriguez, Pablo R. Duchowicz, Gustavo P. Romanelli, José J. Martínez, Laura Juliana Triana Triana |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 44 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |