Preparation and Characterization of Fenofibric Acid-Loaded Electrospun Fibrous Mats
Enikő Bitay, Gergő Tóth, Zoltán-István Szabó · 2026
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Description
Enikő Bitay and co-authors spin a cholesterol drug's active form into dissolvable fiber mats in a 2026 study. Fenofibric acid, the substance fenofibrate becomes in the body, dissolves poorly, which limits how fast it can act. The team mixed it into a water-friendly polymer and used electrospinning, drawing the solution into fine fibers with an electric field.
The mats came out as smooth, even fibers with no defects. Heat tests showed the drug lost its crystal signature inside the fibers, a sign it was spread at the molecular level. In artificial saliva the mats released the drug far faster than the plain crystals did. A mat that dissolves quickly on the tongue or in the mouth could suit patients who struggle with pills, and the method generalizes to other hard-to-dissolve medicines.
Catalog record
| CREATOR | Enikő Bitay, Gergő Tóth, Zoltán-István Szabó |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 20 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |