Comparative essentialome analysis of six Pectobacteriaceae strains using the TNSEEK pipeline identifies conserved and strain-specific fitness determinants
Julie Baltenneck, Loïc Couderc, Jacques Pédron, Guillemette Marot, Areski Flissi, Hélène Touzet, Erwan Gueguen, Marie-Anne Barny, Guy Condemine · 2026
Read Comparative essentialome analysis of six Pectobacteriaceae strains using the TNSEEK pipeline identifies conserved and strain-specific fitness determinants by Julie Baltenneck, Loïc Couderc, Jacques Pédron, Guillemette Marot, Areski Flissi, Hélène Touzet, Erwan Gueguen, Marie-Anne Barny, Guy Condemine (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-13566846.txt.
Description
Julie Baltenneck and co-authors map which genes six rot-causing bacteria cannot live without in work dated two thousand twenty-six. The bacteria rot soft plant tissue and span two genera. A gene-jumping method can find vital genes, but comparing big data sets across strains is hard.
Their pipeline, TNSEEK, automates that comparison end to end. Two hundred twenty-five genes proved vital in all six strains, mostly for basic cell upkeep. Few vital genes were shared at genus level alone, which flags distinct diets between the genera. A large set of one hundred eighty-one genes was vital in single strains only, many of unknown role. Some belong to defense systems and virus remnants in the genome.
Catalog record
| CREATOR | Julie Baltenneck, Loïc Couderc, Jacques Pédron, Guillemette Marot, Areski Flissi, Hélène Touzet, Erwan Gueguen, Marie-Anne Barny, Guy Condemine |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 66 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |