Development of a Multidomain Conceptual Framework for Frozen Shoulder: A Systematic Review Integrating Clinical, Biological, Psychological and Lifestyle-Related Contributors
Santiago Navarro-Ledesma, José Javier Pérez-Montilla, Dina Hamed-Hamed, Fabrizio Brindisino, Filip Struyf · 2026
Read Development of a Multidomain Conceptual Framework for Frozen Shoulder: A Systematic Review Integrating Clinical, Biological, Psychological and Lifestyle-Related Contributors by Santiago Navarro-Ledesma, José Javier Pérez-Montilla, Dina Hamed-Hamed, Fabrizio Brindisino, Filip Struyf (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-13566836.txt.
Description
Santiago Navarro-Ledesma and co-authors build a whole-person frame for frozen shoulder in a 2026 review. Frozen shoulder stiffens and pains the joint, and its drivers span body, mind, and lifestyle. No past frame had joined clinical signs, metabolism, imaging, mood, habits, and inflammation into one phenotyping tool.
The review pooled sixty-three observational studies sorted into spheres of evidence. Clinical studies dominated, with smaller sets for mood, imaging, and metabolism, and one direct study for inflammation. Each study's weight reflected how direct, steady, and sound its evidence was. The final frame keeps five spheres for sorting patients. The authors stress that the weights are exploratory, meant to guide fuller phenotyping rather than settle care.
Catalog record
| CREATOR | Santiago Navarro-Ledesma, José Javier Pérez-Montilla, Dina Hamed-Hamed, Fabrizio Brindisino, Filip Struyf |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 48 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |