The RNA-Binding Protein ELAVL4/HuD Promotes Stress-Associated Tumor Survival in Neuroendocrine Cancers
Kausik Bishayee, Vaishak Kaviyarasan, Sun Young Yoo, Seung Hee Lee, Yong Soo Park · 2026
Read The RNA-Binding Protein ELAVL4/HuD Promotes Stress-Associated Tumor Survival in Neuroendocrine Cancers by Kausik Bishayee, Vaishak Kaviyarasan, Sun Young Yoo, Seung Hee Lee, Yong Soo Park (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-13566736.txt.
Description
Bishayee and co-authors review a protein that helps tumors survive stress in a 2026 paper. Neuroendocrine cancers carry high levels of ELAVL4, also called HuD, a protein that binds RNA. The protein steadies key messages inside cells, which tilts them toward survival. Silencing it in cancer cells and tumors cuts growth and viability, marking it as a lever worth study.
The review maps how HuD props up tumors on several fronts. It helps cells weather oxidative and metabolic stress, boosts self cleaning, and blunts cell death. Each path gives tumors an edge in harsh surroundings. The authors urge deeper work on how HuD acts across cancer types, since blocking it could open a fresh line of attack.
Catalog record
| CREATOR | Kausik Bishayee, Vaishak Kaviyarasan, Sun Young Yoo, Seung Hee Lee, Yong Soo Park |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 45 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |