Melatonin Regulates Growth‐Arrest and DNA‐Damage Genes GADD153, GADD45g and GADD34 in Experimental Varicocele
Esra Önal, Numan Baydilli, Derya Karabulut · 2026
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Description
Önal, Baydilli, and Karabulut test melatonin in rats with a varicocele, a swollen vein flaw that harms the testicle in twenty twenty-six. Forty rats split into control, hormone only, flaw only, and flaw plus hormone groups. The flaw was tied off and left for two months. Melatonin then ran for one week.
Flawed rats showed shrunken testes, worse tissue scores, and stress gene proteins switched on. Key hormones and defense levels sagged while strain markers rose. Melatonin partly reversed each shift in the treated flaw group. Tissue, gene, and blood reads all moved toward normal. The hormone looks like a real remedy here, they say.
Catalog record
| CREATOR | Esra Önal, Numan Baydilli, Derya Karabulut |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 48 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |