Idiopathic Raynaud’s Phenomenon and Vitamin D Deficiency in Children and Adolescents: An Exploratory Single-Center Retrospective Observational Study Throughout the Period 2010–2025
Donato Rigante, Michele Fastiggi, Cristina Guerriero, Marcello Candelli · 2026
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Description
Donato Rigante and three colleagues published a children's health study in two thousand twenty-six on Raynaud's phenomenon and vitamin D. In this condition fingers and toes blanch and ache in the cold. In children it can be an early sign of deeper disease, so causes matter.
The team reviewed sixty-one young patients followed at one Italian centre over fifteen years. About a third had low vitamin D, while most other blood tests were uninformative. Low-vitamin patients had longer illness, worse two-week symptom scores, and more pain at the start. Those found low received vitamin D supplements for at least twelve weeks. The study then tracked whether their Raynaud's severity changed with treatment.
Catalog record
| CREATOR | Donato Rigante, Michele Fastiggi, Cristina Guerriero, Marcello Candelli |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 27 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |