Pharmacological maintenance treatment in older age bipolar disorder

Debbie Zittema, Annemieke Dols · 2026

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Description

Debbie Zittema and Annemieke Dols review, in a 2026 article, long-term drug treatment for bipolar disorder in adults aged fifty and over, a group defined by the illness's link with early aging. Work from a global research initiative and other recent studies is summarized, although no new intervention trials appeared in the prior eighteen months.

Lithium stays the first-choice maintenance drug, but at a lower target blood range for older patients. The authors argue it should not be withheld over fears about future kidney decline. Most proof so far comes from cohort and cross-sectional studies, so prescribers get guidance tempered by clear gaps in trial data for older adults.

Catalog record

CREATORDebbie Zittema, Annemieke Dols
YEAR2026
COLLECTIONPAPERS
FORMATTXT
FILE SIZE20877
LICENSEhttps://creativecommons.org/licenses/by/4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/article/MED/PMC13566370

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