Cancer Cachexia in Advanced Renal Cell Carcinoma: From Molecular Mechanisms to Prognostic Assessment
Yushuang Cui, Yudong Cao, Chen Lin, Jinchao Ma, Shuo Wang, Peng Du · 2026
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Description
Yushuang Cui and co-authors review severe weight and muscle loss in advanced kidney cancer in a 2026 paper. The wasting syndrome, called cachexia, affects roughly a third to three-fifths of these patients. It lowers tolerance for treatment and shortens life, yet kidney-specific guidance stays thin.
The review traces drivers such as body-wide inflammation, changed energy use, and signals sent out by the tumor. For judging risk, scans of muscle mass can join blood markers of inflammation and nutrition in set scores. Care today rests on food support and exercise plans, while targeted drugs may ease part of the wasting. Trials of a blocker for one tumor signal are under way, and the authors urge shared standards for testing.
Catalog record
| CREATOR | Yushuang Cui, Yudong Cao, Chen Lin, Jinchao Ma, Shuo Wang, Peng Du |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 40 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |