Photobiomodulation with 808 nm Laser Light Repairs Mitochondrial Integrity and Normalizes ROS, ATP, and Membrane Depolarization in Aβ-Exposed Primary Neurons in Alzheimer’s Disease Model
Iuliia Golovynska, Binjun Li, Qinglin Chen, Sergii Golovynskyi, Hao Xu, Yurii V. Stepanov, Liudmyla I. Stepanova, Fangrui Lin, Junle Qu, Tymish Y. Ohulchanskyy · 2026
Read Photobiomodulation with 808 nm Laser Light Repairs Mitochondrial Integrity and Normalizes ROS, ATP, and Membrane Depolarization in Aβ-Exposed Primary Neurons in Alzheimer’s Disease Model by Iuliia Golovynska, Binjun Li, Qinglin Chen, Sergii Golovynskyi, Hao Xu, Yurii V. Stepanov, Liudmyla I. Stepanova, Fangrui Lin, Junle Qu, Tymish Y. Ohulchanskyy (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-13565913.txt.
Description
Iuliia Golovynska and nine co-authors shine near-infrared light on poisoned brain cells to test whether it rescues their power plants, in a 2026 study. Alzheimer disease is increasingly seen as a failure of mitochondria, the cell’s energy hubs, which fragment and falter. Light treatment at gentle doses had protected brain cells in animal models, but whether fixing the mitochondrial web is required for that rescue was unknown.
The team bathed mouse hippocampal neurons in the amyloid protein that marks the disease, then irradiated them with 808-nanometer light at a set dose. Shape maps of the mitochondrial network, plus readings of reactive oxygen, energy currency, and membrane voltage, showed whether the light restored normal function. Proof of mechanism matters before shining light into human trials.
Catalog record
| CREATOR | Iuliia Golovynska, Binjun Li, Qinglin Chen, Sergii Golovynskyi, Hao Xu, Yurii V. Stepanov, Liudmyla I. Stepanova, Fangrui Lin, Junle Qu, Tymish Y. Ohulchanskyy |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 58 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |