Application of Mesenchymal Stromal Cells and Their Exosomes in Neurodegenerative Diseases and Lysosomal Storage Diseases

Aisylu I. Ayupova, Angelina S. Sidorova, Ekaterina A. Luzina, Albert A. Sufianov, Galina Z. Sufianova, Azat M. Zaynutdinov, Albert A. Rizvanov, Valeriya V. Solovyeva · 2026

Read Application of Mesenchymal Stromal Cells and Their Exosomes in Neurodegenerative Diseases and Lysosomal Storage Diseases by Aisylu I. Ayupova, Angelina S. Sidorova, Ekaterina A. Luzina, Albert A. Sufianov, Galina Z. Sufianova, Azat M. Zaynutdinov, Albert A. Rizvanov, Valeriya V. Solovyeva (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-13564811.txt.

Description

Stem-like stromal cells calm inflammation and ferry missing enzymes, two talents that brain diseases sorely need. Aisylu Ayupova and co-authors review their use across nerve degeneration and storage disorders in a 2026 paper.

The cells work mainly by secreting helpful factors, tuning the immune system, fighting oxidative stress, and waking the cell's recycling machinery. In storage diseases they can hand working enzymes to deficient neighbors. Evidence is gathered disease by disease, from ALS and Alzheimer to multiple sclerosis. The cells' shed vesicles offer a cell-free alternative that may reach the brain more safely. Blood clotting risks, dosing chaos, and missing large trials temper the promise, and the authors map adjunct roles beside gene therapy.

Catalog record

CREATORAisylu I. Ayupova, Angelina S. Sidorova, Ekaterina A. Luzina, Albert A. Sufianov, Galina Z. Sufianova, Azat M. Zaynutdinov, Albert A. Rizvanov, Valeriya V. Solovyeva
YEAR2026
COLLECTIONPAPERS
FORMATTXT
FILE SIZE113 KB
VERSION1.0
LICENSECC BY 4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/articles/PMC13564811

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