The Role of Transcriptional and Atypical Cyclin-Dependent Protein Kinases in Melanoma
Jonatan Kaszubski, Maciej Gagat, Agata Wawrzyniak, Agnieszka Żuryń · 2026
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Description
Kaszubski and co-authors review a family of enzymes as possible drug targets in melanoma in a 2026 paper. Melanoma is the skin cancer with the highest death rate. New immune and targeted drugs have changed care, but tumors often resist them, so teams still seek fresh targets. The enzymes in focus help control basic cell work.
Most study has gone to the members that time the cell cycle. The review turns instead to members that guide gene reading and to less typical members, such as one that matters in the nervous system. The authors weigh gains and risks of blocking these enzymes, and how such drugs might pair with other treatments.
Catalog record
| CREATOR | Jonatan Kaszubski, Maciej Gagat, Agata Wawrzyniak, Agnieszka Żuryń |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 62 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |