Decoding Sebaceous Gland Biology Through Experimental Models: Progress, Limitations, and Future Directions
Stefania Briganti, Sarah Mosca, Monica Ottaviani, Enrica Flori · 2026
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Description
Stefania Briganti and three co-authors survey the lab models used to study sebaceous glands, the small oil glands of the skin, in a review published in two thousand twenty-six. These glands keep skin in balance through oil output, immune work, and ties with skin microbes. When they fail, acne and other skin diseases can follow. Models range from animals and human skin samples to grown sebocyte cells.
New three-dimensional models are the high point: cell balls, organoids grown from stem cells, and skin-like builds that include the glands. They copy real gland form and work far better than flat cell sheets. Still, most models lack full cell maturity and miss immune and blood vessel parts. The authors chart what each model does well and where the field must go next.
Catalog record
| CREATOR | Stefania Briganti, Sarah Mosca, Monica Ottaviani, Enrica Flori |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 50 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |