Gut microbiota dynamics and metabolic pathways associated with bleomycin-induced pulmonary fibrosis progression
Jinpeng Cong, Wenjuan Xu, Yuzhu Zhang, Xiaoqian Ding, Shichao Cui, Xiaosa Chi, Xiaohui Yang · 2026
Read Gut microbiota dynamics and metabolic pathways associated with bleomycin-induced pulmonary fibrosis progression by Jinpeng Cong, Wenjuan Xu, Yuzhu Zhang, Xiaoqian Ding, Shichao Cui, Xiaosa Chi, Xiaohui Yang (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-13564393.txt.
Description
Jinpeng Cong and six co-authors track, in a 2026 study, how gut microbes shift as lung scarring grows in mice. Pulmonary fibrosis stiffens the lungs as scar tissue and excess matrix pile up. A gut-lung link is now suspected in lung diseases, but stage-by-stage maps of gut microbes were thin. The team gave mice bleomycin, a drug that scars lungs, then read stool microbes at set stages.
Samples came at baseline, at day seven, and at day fourteen. Lung checks confirmed that scarring grew across those stages. Gut mixes shifted by stage: mucus-linked microbe groups fell, while two other groups grew. The work the microbes could do shifted too, with early dips in food and sugar pathways and late rises in starch use and bile production. The authors warn that the links are maps, not proof of cause.
Catalog record
| CREATOR | Jinpeng Cong, Wenjuan Xu, Yuzhu Zhang, Xiaoqian Ding, Shichao Cui, Xiaosa Chi, Xiaohui Yang |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 34 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |