Context-dependent interactions between variable-loop pulsed field ablation and cardiac implantable electronic devices: a controlled preclinical study
Masateru Takigawa, Ryosuke Kato, Iwanari Kawamura, Megumi Toda, Masaki Honda, Miho Negishi, Ryo Tateishi, Junji Yamaguchi, Kentaro Goto, Takuro Nishimura, Susumu Tao, Shinsuke Miyazaki, Tetsuo Sasano · 2026
Read Context-dependent interactions between variable-loop pulsed field ablation and cardiac implantable electronic devices: a controlled preclinical study by Masateru Takigawa, Ryosuke Kato, Iwanari Kawamura, Megumi Toda, Masaki Honda, Miho Negishi, Ryo Tateishi, Junji Yamaguchi, Kentaro Goto, Takuro Nishimura, Susumu Tao, Shinsuke Miyazaki, Tetsuo Sasano (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-13564213.txt.
Description
Pulsed field ablation treats a racing heart with short electric pulses instead of heat, and its use is spreading to new targets in the heart's upper chambers. Takigawa and co-authors asked what those pulses do to pacemakers and defibrillators already implanted in a patient. In a pig study, thirteen animals received modern device systems and seven of them then had ablation at several sites, including directly over exposed defibrillator coils.
Ablation in the left atrium, away from device parts, caused no critical failures, though a few settings drifted slightly. In the right atrium and the big vein nearby, disturbances and one dislodged lead traced mostly to the catheter bumping the leads, not the pulses. Pulses over the bare coils changed local readings without breaking the devices, and a leadless pacemaker and a skin-level defibrillator stayed steady. The lesson: the risk depends on where and how the energy lands.
Catalog record
| CREATOR | Masateru Takigawa, Ryosuke Kato, Iwanari Kawamura, Megumi Toda, Masaki Honda, Miho Negishi, Ryo Tateishi, Junji Yamaguchi, Kentaro Goto, Takuro Nishimura, Susumu Tao, Shinsuke Miyazaki, Tetsuo Sasano |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 47 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |