Serum serotonin and its association with glycaemic indices and haemoglobin in adults with migraine: a comparative cross-sectional study
Anusha Jaganathan, Kalpana Radhakrishnan, Mohamed Azarudeen Musthak Ali, Robert Wilson Sundaram, Arunan Subbiah · 2026
Read Serum serotonin and its association with glycaemic indices and haemoglobin in adults with migraine: a comparative cross-sectional study by Anusha Jaganathan, Kalpana Radhakrishnan, Mohamed Azarudeen Musthak Ali, Robert Wilson Sundaram, Arunan Subbiah (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/PMC13563856.txt.
Description
Anusha Jaganathan and four colleagues compare blood serotonin in adults with migraine against healthy peers, and probe its ties to sugar and blood measures. Serotonin sits at the heart of migraine biology, yet its links with metabolism and haemoglobin were murky. Their 2026 study enrolled 74 migraine patients diagnosed by international criteria and 82 controls at a teaching hospital. Fasting glucose, the sugar marker, haemoglobin, thyroid signal, blood pressure, and serotonin were recorded, then related with age-adjusted statistics.
The gap startled: serotonin averaged 10.72 nanograms per millilitre in migraine against 88.43 in controls, and it survived age adjustment. The migraine group ran older, with higher pressure, pulse, glucose, and sugar markers, and lower haemoglobin. Serotonin fell as sugar and pressure rose, and climbed with haemoglobin. Average glucose, haemoglobin, and age each predicted serotonin independently. The authors label the cross-sectional findings exploratory and ask for follow-up studies tracking patients over time.
Catalog record
| CREATOR | Anusha Jaganathan, Kalpana Radhakrishnan, Mohamed Azarudeen Musthak Ali, Robert Wilson Sundaram, Arunan Subbiah |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 31611 |
| LICENSE | https://creativecommons.org/licenses/by/4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |