Effect of acetylsalicylic acid (ASA) pretreatment on white noise-induced stress model in rats
Deniz Aktaran Bala, Ibrahim Akyazi, Evren Eraslan, Feraye Esen Gursel, Sibel Akyol, Nuran Dariyerli · 2026
Read Effect of acetylsalicylic acid (ASA) pretreatment on white noise-induced stress model in rats by Deniz Aktaran Bala, Ibrahim Akyazi, Evren Eraslan, Feraye Esen Gursel, Sibel Akyol, Nuran Dariyerli (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/PMC13563717.txt.
Description
Deniz Aktaran Bala and five colleagues test whether aspirin can shield the rat brain from the stress of blaring white noise. Noise is a general stressor that ramps up reactive oxygen species, and the amygdala and hippocampus, the brain's alarm and memory hubs, are easily hurt by damage. The 2026 experiment pretreated rats with acetylsalicylic acid before noise exposure, then read chemistry across blood and five brain regions. Measures included a fat-damage marker, vitamin C, stress hormones, blood chemistry, and inflammatory signals.
One result stood out. The damage marker in the amygdala ran lower in pretreated, noise-exposed rats than in every other group. Most other regions and signals barely moved. Vitamin C in whole brain dipped in the pretreated stressed group, and tumour necrosis factor rose with aspirin. Blood chemistry stayed largely flat. The authors report a narrow, region-specific protection, not a broad shield.
Catalog record
| CREATOR | Deniz Aktaran Bala, Ibrahim Akyazi, Evren Eraslan, Feraye Esen Gursel, Sibel Akyol, Nuran Dariyerli |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 31405 |
| LICENSE | https://creativecommons.org/licenses/by/4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |