Raman and surface-enhanced Raman spectroscopy for intraoperative cancer diagnostics: sentinel lymph node biopsy, biomarkers and translational challenges
Jiaqi Feng, Chunyan Li, Xiaowei Jiang, Lizhi Zhou, Yifei Jiang, Binge Deng · 2026
Read Raman and surface-enhanced Raman spectroscopy for intraoperative cancer diagnostics: sentinel lymph node biopsy, biomarkers and translational challenges by Jiaqi Feng, Chunyan Li, Xiaowei Jiang, Lizhi Zhou, Yifei Jiang, Binge Deng (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-13563144.txt.
Description
Jiaqi Feng and co-authors review a light-based method for judging lymph nodes while surgery is still underway. The first node a tumor drains to decides how far cancer has spread, but quick checks during the operation can miss tiny deposits and lean on human judgment. Raman spectroscopy reads a tissue's molecular fingerprint from scattered light, without dyes or destruction.
Enhanced versions of the method amplify faint signals enough to hunt biomarkers of spread, and learning algorithms sort the complex spectra fast and objectively. The review walks through uses in breast, thyroid, and skin cancers, in plain and enhanced forms, weighing speed and accuracy against shallow light penetration. The authors close on the hurdles between promising studies and routine clinical adoption.
Catalog record
| CREATOR | Jiaqi Feng, Chunyan Li, Xiaowei Jiang, Lizhi Zhou, Yifei Jiang, Binge Deng |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 89 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |