Effect of intrinsic sphincter deficiency on treatment success following urethral bulking with polyacrylamide hydrogel
Bertie Geng, Layla Joudeh, Ayanna Garland, Elizabeth J. Geller · 2026
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Description
A gel injection that plumps the urethra can stop stress leaks, and a 2026 study by Bertie Geng and co-authors asks whether a weak sphincter muscle undermines the fix. That weakness, intrinsic sphincter deficiency, is known to lower success for several leak treatments.
Records covered 171 women treated with polyacrylamide hydrogel between 2022 and 2024, after exclusions. About twelve percent met the pressure-based definition of the deficiency. Those women were older and received slightly more gel. Success meant no leaks or clearly improved leaks at first follow-up. The comparison between the two groups speaks to counseling: whether a weak sphincter should steer women toward a different operation or simply toward modest expectations.
Catalog record
| CREATOR | Bertie Geng, Layla Joudeh, Ayanna Garland, Elizabeth J. Geller |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 16 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |