TTP‐Like Syndrome and Subsequent Non‐Aneurysmal Subarachnoid Hemorrhage in HbSC Disease: A Case Report
Benjamin Vieten, Jan Vorwerk, Jan Morf, Alice Dauth, Stefan Sondermann, Peter Schramm, Tobias Graf, Nikolas von Bubnoff, Lorenz Oelschläger, Cyrus Khandanpour · 2026
Read TTP‐Like Syndrome and Subsequent Non‐Aneurysmal Subarachnoid Hemorrhage in HbSC Disease: A Case Report by Benjamin Vieten, Jan Vorwerk, Jan Morf, Alice Dauth, Stefan Sondermann, Peter Schramm, Tobias Graf, Nikolas von Bubnoff, Lorenz Oelschläger, Cyrus Khandanpour (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-13563050.txt.
Description
Benjamin Vieten and nine colleagues describe a severe case in a 26-year-old man with HbSC sickle cell disease. An infection triggered a crisis of blocked vessels, acute chest syndrome, a sharp drop in platelets, and breakdown of red cells. Kidney injury and a very high level of a damage enzyme added to the picture. The pattern first raised concern for a rare clotting disorder, but the key enzyme for that disorder was not much reduced.
The team read the episode as a syndrome like that disorder, with fat embolism as a key alternative. Exchange of red cells and plasma, a targeted drug, antibiotics, and dialysis led to recovery of blood and kidneys. Months later the man suffered bleeding around the brain, with lasting nerve damage.
Catalog record
| CREATOR | Benjamin Vieten, Jan Vorwerk, Jan Morf, Alice Dauth, Stefan Sondermann, Peter Schramm, Tobias Graf, Nikolas von Bubnoff, Lorenz Oelschläger, Cyrus Khandanpour |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 22 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |