Inhibition or induction of gastrointestinal tumors by ferroptosis and intervention by herbal extracts (Review)
Defei Yin, Qinghua Li, Junwei Liang, Xiaoyan Yan, Dajuan Sun · 2026
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Description
Defei Yin and co-authors present a 2026 review of ferroptosis, an iron-linked form of cell death, in gut cancers. The death path runs on iron overload and fat damage inside cells. In tumors of the food pipe, stomach, liver, and bowel, the same path can cut both ways: it can kill tumor cells or help them resist care. The review gathers the known switches of the path.
Iron handling, fat damage, and one shield system of the cell form the core trio. Shared patterns run across gut tumors, with local twists per organ. Plant extracts that spark the death path get a full survey as candidate drugs. The authors also list what blocks clinic use so far. Clearer rules for when to spark or block the path could sharpen care choices.
Catalog record
| CREATOR | Defei Yin, Qinghua Li, Junwei Liang, Xiaoyan Yan, Dajuan Sun |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 41 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |