Prognostic analysis of epithelial ovarian cancer patients with normal CA125 level: a population-based comparative study
Chuanzhong Liu, Liying Zhang, Yibao Huang, Haijuan Shi, Zhijun Yang · 2026
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Description
Chuanzhong Liu and four colleagues study the minority of ovarian cancer patients whose main blood marker stays normal, and build a tool to predict their survival. Most epithelial ovarian cancers raise the marker CA125, so guidance built on typical cases may mislead them. The 2026 team pulled 13,068 patients from the United States SEER registry and added 138 patients from their own hospital as a check. Patients with normal levels tended to live longer.
A survival model drawn as a nomogram chart weighed what mattered most for the normal-marker group. Age counted, as did how far the cancer had spread, the tumour's tissue type, and whether lymph nodes were removed. Each factor adds points toward a personal survival estimate. The authors offer the chart as a counselling aid for a group that marker-based monitoring serves poorly, since their disease can progress without tripping the usual alarm.
Catalog record
| CREATOR | Chuanzhong Liu, Liying Zhang, Yibao Huang, Haijuan Shi, Zhijun Yang |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 25807 |
| LICENSE | https://creativecommons.org/licenses/by/4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |