Structural basis of fatty acid activation and transport by human FATP2

Ao Li, Junhui Shi, Xiaoyan Xu, Yu Yang, Shan Feng, Dan Ma · 2026

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Description

Fatty acid transport proteins (FATPs) are responsible for efficient uptake of fatty acids (FAs), essential biomolecules that play critical roles in development and growth. However, the lack of three-dimensional structures of FATPs has hindered our understanding of their mechanisms. Here, we report two cryo-EM structures of human FATP2a: wild-type (WT) FATP2a in intermediate state at 2.

Catalog record

CREATORAo Li, Junhui Shi, Xiaoyan Xu, Yu Yang, Shan Feng, Dan Ma
YEAR2026
COLLECTIONPAPERS
FORMATTXT
FILE SIZE56 KB
VERSION1.0
LICENSECC BY 4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/articles/PMC13562550

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