From oral infection to pulmonary inflammation: periodontal pathogens and their potential role in COPD susceptibility
Xiaohao Liu, Yan Chai, Fengxiang Shi, Bingchun Li, Jiawei Zeng, Jiaming Bi, Shuaimei Xu, Buling Wu · 2026
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Description
Xiaohao Liu and co-authors study whether gum disease is linked to chronic obstructive pulmonary disease, or COPD, in this 2026 paper. Both conditions involve long term inflammation, and both are common in older adults. The authors ask whether disease in the mouth helps drive disease in the lungs.
The team used survey data, genetic methods, cell tests, and a rat model. They found links between reported gum disease and COPD, with blood pressure and flossing changing the link. Cells exposed to two gum bacteria made more signals linked to inflammation. The rat model showed worse lung inflammation when both diseases were present.
Catalog record
| CREATOR | Xiaohao Liu, Yan Chai, Fengxiang Shi, Bingchun Li, Jiawei Zeng, Jiaming Bi, Shuaimei Xu, Buling Wu |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 68 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |