Nutritional remission without mucosal healing in type II refractory celiac disease: a case report

Om Kolthoum Sallem, Asma Sabbek, Nabil Ben Chaabène, Leila Safer · 2026

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Description

Om Kolthoum Sallem and co-authors report a difficult celiac disease case from 2026 in a 56-year-old Tunisian woman. Her illness had become type two refractory celiac disease, a rare pre-cancerous form that no longer responds to a gluten-free diet. She arrived severely malnourished at thirty-four kilograms, wheelchair dependent, with up to twenty stools a day.

Scans found no lymphoma, but gut biopsies showed total villus flattening and a large share of abnormal immune cells. Feeding by vein, then by tube, plus a targeted steroid in open capsules, slowly restored her. By six months she had gained twenty-six kilograms and her blood protein had normalized, though biopsies still showed flat villi and the abnormal cells. Recovery and gut healing can part ways.

Catalog record

CREATOROm Kolthoum Sallem, Asma Sabbek, Nabil Ben Chaabène, Leila Safer
YEAR2026
COLLECTIONPAPERS
FORMATTXT
FILE SIZE25 KB
VERSION1.0
LICENSECC BY 4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/articles/PMC13561813

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