Life course adiposity and risk of incident osteoporosis: a prospective cohort study from the UK Biobank

Huimin Liu, Jicun Zhu, Qiang Zhang, Jiajun Chen, Ruoyao Huang · 2026

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Description

Huimin Liu and four co-authors follow body fat across the whole life span and later bone thinning risk, in a United Kingdom cohort study from 2026. Birth size, child body size, and adult weight may each shape bone health, but their shares were unclear.

More than three hundred fifty thousand adults were tracked for about sixteen years. Low birth weight, a thin child frame, and low adult weight each raised bone thinning risk, with adult weight the strongest. Much of the early life effect ran through adult weight. Blood protein scans found scores of go between proteins that link fat, hormones, and bone.

Catalog record

CREATORHuimin Liu, Jicun Zhu, Qiang Zhang, Jiajun Chen, Ruoyao Huang
YEAR2026
COLLECTIONPAPERS
FORMATTXT
FILE SIZE37 KB
VERSION1.0
LICENSECC BY 4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/articles/PMC13561790

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