Lymphocytic Variant Hypereosinophilic Syndrome Overlaps with Angioimmunoblastic T-Cell Lymphoma: A Case Report and Literature Review

Nabil Belfeki, Omaima El Koudssi, Pierre Isnard, Guillaume Lefevre · 2026

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Description

IntroductionLymphocytic-variant of hypereosinophilic syndrome (L-HES) is a clonal T-cell disorder driven by an aberrant Th2 response, typically featuring CD3- CD4+ T-cell expansion, eosinophil-mediated tissue injury, most commonly skin lesions, and lymphadenopathy. Angioimmunoblastic T-cell lymphoma (AITL) is an aggressive peripheral T-cell lymphoma of follicular helper T-cell origin; it can present with similar clinical features such as lymphadenopathy, rash and eosinophilia.

Catalog record

CREATORNabil Belfeki, Omaima El Koudssi, Pierre Isnard, Guillaume Lefevre
YEAR2026
COLLECTIONPAPERS
FORMATTXT
FILE SIZE11 KB
VERSION1.0
LICENSECC BY 4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/articles/PMC13561141

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