Timing of anticoagulation after emergency endovascular therapy for acute ischaemic stroke with atrial fibrillation (TIMERS): protocol for a randomised controlled trial
Yibing Guo, Xiaole Jia, Wanqing Liu, Wanwan Zhang, Xiao Dong, Ran Meng, Hongrui Ma, Guiyun Cui, Yanbo Cheng, Tingyu Yi, Jiheng Hao, Yufeng Jiang, Xunming Ji, Yu Feng, Chuanjie Wu · 2026
Read Timing of anticoagulation after emergency endovascular therapy for acute ischaemic stroke with atrial fibrillation (TIMERS): protocol for a randomised controlled trial by Yibing Guo, Xiaole Jia, Wanqing Liu, Wanwan Zhang, Xiao Dong, Ran Meng, Hongrui Ma, Guiyun Cui, Yanbo Cheng, Tingyu Yi, Jiheng Hao, Yufeng Jiang, Xunming Ji, Yu Feng, Chuanjie Wu (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-13560989.txt.
Description
Yibing Guo and a team of co-authors published a trial protocol in 2026 on when to restart blood thinners after a stroke treated by clot removal. Patients with a fluttering heart rhythm need these drugs to prevent the next stroke, but starting too soon risks bleeding into the injured brain. Those who had clot-removal treatment are at the highest risk on both sides, yet earlier trials mostly left them out.
The trial will enroll 438 such patients across many centers and assign them by chance to start within four days or to wait five to fourteen days. The main yardstick, at ninety days, combines new stroke, serious brain bleeding, and death. Function and quality of life are also tracked. The answer should settle a daily dilemma on stroke wards.
Catalog record
| CREATOR | Yibing Guo, Xiaole Jia, Wanqing Liu, Wanwan Zhang, Xiao Dong, Ran Meng, Hongrui Ma, Guiyun Cui, Yanbo Cheng, Tingyu Yi, Jiheng Hao, Yufeng Jiang, Xunming Ji, Yu Feng, Chuanjie Wu |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 26 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |