Associations of three metabolic biomarkers with the risk of cardiometabolic multimorbidity: a national prospective study
Yan Jiang, Mengdie Liu, Hua Chen, Fengpei Zhang, Si Liu, Xin Li, Ting Guo, Zhiteng Xiong, Qihui Shen, Xiaoyun Xiong · 2026
Read Associations of three metabolic biomarkers with the risk of cardiometabolic multimorbidity: a national prospective study by Yan Jiang, Mengdie Liu, Hua Chen, Fengpei Zhang, Si Liu, Xin Li, Ting Guo, Zhiteng Xiong, Qihui Shen, Xiaoyun Xiong (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/PMC13560287.txt.
Description
Yan Jiang and colleagues test three metabolic blood indices as predictors of cardiometabolic multimorbidity, the pileup of heart and metabolic diseases, in Chinese adults. Their 2026 prospective study uses the national aging cohort CHARLS and follows 5,666 participants free of the combined outcome at baseline. The indices mix triglycerides, glucose, cholesterol fractions, and inflammation markers in different recipes.
During follow-up, 473 participants, 8.3 percent of the group, developed multimorbidity. Higher values of all three indices tracked with higher risk in adjusted survival models. The inflammation-bearing index performed best: its top quarter carried about two and a half times the risk of its bottom quarter in the reported hazard ratios. Discrimination stayed modest, with the best index reaching an area under the curve of 0.670 in the ROC analysis. Age and sex did not modify the links. The authors back metabolic indices for early risk sorting.
Catalog record
| CREATOR | Yan Jiang, Mengdie Liu, Hua Chen, Fengpei Zhang, Si Liu, Xin Li, Ting Guo, Zhiteng Xiong, Qihui Shen, Xiaoyun Xiong |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 37055 |
| LICENSE | https://creativecommons.org/licenses/by/4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |