Competing risks of AIDS and death in people living with HIV: a left-truncated and right-censored retrospective cohort study in Khuzestan, Iran (2001–2022)
Kayvan Kajkolahi, Mohsen Askarishahi, Kazem Alizadeh Barzian, Nima Daneshi, Mohammad Sadegh Loeloe · 2026
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Description
Kayvan Kajkolahi and four colleagues estimate the competing risks of AIDS progression and death among people living with HIV in Khuzestan, Iran. Their 2026 retrospective cohort uses counseling center records from 2001 to 2022, analyzed with methods that respect delayed entry into care and the fact that death can preclude an AIDS diagnosis. Late diagnosis, a CD4 count under 350 at baseline, anchors the analysis.
Across follow-up, the cumulative incidence of death outran that of AIDS in most periods. Late diagnosis doubled the hazard of death and raised the AIDS hazard significantly as well. Age fifty or over, male sex, and tuberculosis co-infection each independently predicted death. The authors stress that registry cohorts mislead when analysts ignore left truncation. Their practical message is early testing and fast linkage to care, since late arrival drives both bad outcomes.
Catalog record
| CREATOR | Kayvan Kajkolahi, Mohsen Askarishahi, Kazem Alizadeh Barzian, Nima Daneshi, Mohammad Sadegh Loeloe |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 55474 |
| LICENSE | https://creativecommons.org/licenses/by/4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |