Implementing an exercise intervention for sarcopenia in oldest-old nursing home residents: protocol for a pragmatic cluster-randomized controlled trial (SCOPE Study)
Cheng Xiang, Lu Li, Jianzhi Zhao, Yuwen Zhou, Wenye Cai, Yixi Guo, Ziru Yang, Xin An, Changxu Gu, Run Ding, Xucheng Wu, Yincun Wang, Di Wang, Shen Xu, Zuyun Liu, Ying Gao · 2026
Read Implementing an exercise intervention for sarcopenia in oldest-old nursing home residents: protocol for a pragmatic cluster-randomized controlled trial (SCOPE Study) by Cheng Xiang, Lu Li, Jianzhi Zhao, Yuwen Zhou, Wenye Cai, Yixi Guo, Ziru Yang, Xin An, Changxu Gu, Run Ding, Xucheng Wu, Yincun Wang, Di Wang, Shen Xu, Zuyun Liu, Ying Gao (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-13560151.txt.
Description
Cheng Xiang and co-authors publish the protocol for the SCOPE trial, a study of exercise for muscle loss in the oldest nursing home residents. Their 2026 paper notes that sarcopenia, the age-related loss of muscle and strength, hits nursing home residents hardest. Past exercise evidence comes mostly from healthier community dwellers, not frail people in long-term care.
The trial plans to enroll 104 residents aged 75 and over in Hangzhou, China. Whole buildings are assigned to one of four arms: modified Baduanjin, resistance training, both, or usual care. Trained caregivers deliver the 48-week program. The study tests both health effects and real-world feasibility. Four groups run side by side over the study period.
Catalog record
| CREATOR | Cheng Xiang, Lu Li, Jianzhi Zhao, Yuwen Zhou, Wenye Cai, Yixi Guo, Ziru Yang, Xin An, Changxu Gu, Run Ding, Xucheng Wu, Yincun Wang, Di Wang, Shen Xu, Zuyun Liu, Ying Gao |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 68 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |