Ethosomal nanocarrier encapsulating curcumin for antimicrobial photodynamic therapy: efficacy analysis against mature Streptococcus mutans biofilm
Alireza Partoazar, Sima Shahabi, Shima Afrasiabi · 2026
Read Ethosomal nanocarrier encapsulating curcumin for antimicrobial photodynamic therapy: efficacy analysis against mature Streptococcus mutans biofilm by Alireza Partoazar, Sima Shahabi, Shima Afrasiabi (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/PMC13560117.txt.
Description
Alireza Partoazar, Sima Shahabi, and Shima Afrasiabi load curcumin into ethosome nanocarriers to strengthen light-activated therapy against mature dental biofilm. Their 2026 laboratory study targets Streptococcus mutans, a bacterium central to plaque and tooth decay. Photodynamic therapy often fails because the light-sensitive drug cannot penetrate thick biofilm, and toxicity limits dosing.
The ethosomes formed spheres averaging about 191 nanometers across and trapped most of the curcumin offered during preparation. Tests on human gum fibroblasts showed the carrier was gentle on healthy cells. Once lit by LED light, the loaded carrier cut mature biofilm by roughly forty percent in the reported assay, statistically close to a strong sodium hypochlorite rinse. Microscopy showed bacterial cells breaking apart after treatment. The authors argue the carrier deserves further study, especially for older, stubborn biofilms.
Catalog record
| CREATOR | Alireza Partoazar, Sima Shahabi, Shima Afrasiabi |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 32467 |
| LICENSE | https://creativecommons.org/licenses/by/4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |