Multi-omics profiling of circulating proteins and metabolites in persistent atrial fibrillation: VDAC1 identified as a candidate circulating protein
Jun Wang, Xiaozhen Chen, Zilan Zhang, Chun Gui · 2026
Read Multi-omics profiling of circulating proteins and metabolites in persistent atrial fibrillation: VDAC1 identified as a candidate circulating protein by Jun Wang, Xiaozhen Chen, Zilan Zhang, Chun Gui (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-13560034.txt.
Description
Jun Wang and co-authors profile blood proteins and metabolites in persistent atrial fibrillation in a 2026 study. The common rhythm disorder involves metabolic change and mitochondrial damage in the atrium. Few studies had layered multiple omics on patient plasma.
Blood drawn from the heart's own sinus in patients with fibrillation and a comparison rhythm disorder was split between deep profiling in a subset and targeted validation in the rest. Over three thousand proteins were quantified, with a few hundred differing between groups. One mitochondrial channel protein, VDAC1, emerged as a candidate marker. A blood signature of fibrillation could ease diagnosis and monitoring.
Catalog record
| CREATOR | Jun Wang, Xiaozhen Chen, Zilan Zhang, Chun Gui |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 40 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |