CONUT score and Naples prognostic score (NPS) for dual prediction of survival and radiation toxicity in locally advanced non-small cell lung cancer with chemoradiotherapy

Shuyang Chen, Xin Qu, Jingyi Wang, Zhongyu Li, Yang Cao, Chunbo Wang · 2026

Read CONUT score and Naples prognostic score (NPS) for dual prediction of survival and radiation toxicity in locally advanced non-small cell lung cancer with chemoradiotherapy by Shuyang Chen, Xin Qu, Jingyi Wang, Zhongyu Li, Yang Cao, Chunbo Wang (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/PMC13559416.txt.

Description

Shuyang Chen and colleagues test whether two blood-based scores can predict both survival and radiation side effects in locally advanced non-small cell lung cancer treated with chemoradiotherapy. Their 2026 study followed 126 patients at Harbin Medical University Cancer Hospital treated between March 2019 and December 2022. The CONUT score and the Naples prognostic score both blend nutrition and inflammation markers from routine blood work.

Median follow-up reached 53 months. High scores on either measure independently predicted shorter progression-free and overall survival in adjusted models. Their accuracy for survival at two to five years sat in a similar range, with areas under the curve around 0.8 in several of the reported checks. High scores also flagged patients more likely to suffer grade 2 or worse lung or esophagus inflammation from radiation. The authors propose the pair as cheap dual-purpose tools for planning treatment and counseling patients.

Catalog record

CREATORShuyang Chen, Xin Qu, Jingyi Wang, Zhongyu Li, Yang Cao, Chunbo Wang
YEAR2026
COLLECTIONPAPERS
FORMATTXT
FILE SIZE42534
LICENSEhttps://creativecommons.org/licenses/by/4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/article/MED/PMC13559416

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