Development of a peripheral lung cancer model in rabbits using thoracoscopic-guided bronchoscopic inoculation
Taek Yong Ko, Jin Hyuk Choi, Sun-Ju Oh, Dahae Yang, Ju Young Na, Sooyong Lee, Jesang Yu · 2026
Read Development of a peripheral lung cancer model in rabbits using thoracoscopic-guided bronchoscopic inoculation by Taek Yong Ko, Jin Hyuk Choi, Sun-Ju Oh, Dahae Yang, Ju Young Na, Sooyong Lee, Jesang Yu (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/PMC13559393.txt.
Description
Taek Yong Ko and colleagues describe a method for growing a lung tumor at a chosen spot near the edge of a rabbit's lung, a platform for testing surgery and focused radiation. Their 2026 paper tackles a practical problem: injected tumor cells often leak and spread through the chest instead of forming one local mass. The team paired a bronchoscope inside the airway with a thoracoscope watching from outside.
New Zealand White rabbits received VX2 tumor cells through a thin catheter placed under direct vision. Cells mixed with lipiodol, an oily contrast agent, behaved best: four of five rabbits on the refined protocol grew tumors, and three tumors sat exactly at the intended peripheral site. Cells injected alone grew invasively without staying local. Tissue examination confirmed cancer at the target. The authors offer the model for preclinical testing while noting it still needs refinement.
Catalog record
| CREATOR | Taek Yong Ko, Jin Hyuk Choi, Sun-Ju Oh, Dahae Yang, Ju Young Na, Sooyong Lee, Jesang Yu |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 30224 |
| LICENSE | https://creativecommons.org/licenses/by/4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |